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Combined multiphoton imaging and biaxial tissue extension for quantitative analysis of geometric fiber organization in human reticular dermis

The geometric organization of collagen fibers in human reticular dermis and its relationship to that of elastic fibers remain unclear. The tight packing and complex intertwining of dermal collagen fibers hinder accurate analysis of fiber orientation. We hypothesized that combined multiphoton microsc...

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Detalles Bibliográficos
Autores principales: Ueda, Maho, Saito, Susumu, Murata, Teruasa, Hirano, Tomoko, Bise, Ryoma, Kabashima, Kenji, Suzuki, Shigehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650477/
https://www.ncbi.nlm.nih.gov/pubmed/31337875
http://dx.doi.org/10.1038/s41598-019-47213-5