Tryptophan Oxidation in the UQCRC1 Subunit of Mitochondrial Complex III (Ubiquinol-Cytochrome C Reductase) in a Mouse Model of Myodegeneration Causes Large Structural Changes in the Complex: A Molecular Dynamics Simulation Study

Muscle diseases display mitochondrial dysfunction and oxidative damage. Our previous study in a cardiotoxin model of myodegeneration correlated muscle damage with mitochondrial dysfunction, which in turn entailed altered mitochondrial proteome and oxidative damage of mitochondrial proteins. Proteomi...

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Detalles Bibliográficos
Autores principales: Unni, Sruthi, Thiyagarajan, S., Srinivas Bharath, M. M., Padmanabhan, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650490/
https://www.ncbi.nlm.nih.gov/pubmed/31337785
http://dx.doi.org/10.1038/s41598-019-47018-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650490/
https://www.ncbi.nlm.nih.gov/pubmed/31337785
http://dx.doi.org/10.1038/s41598-019-47018-6

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