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Circulating levels of PD-L1 and Galectin-9 are associated with patient survival in surgically treated Hepatocellular Carcinoma independent of their intra-tumoral expression levels

Tumor expression of immune co-inhibitory ligands, such as PD-L1 and Galectin-9, have potential prognostic value in Hepatocellular Carcinoma (HCC). Circulating levels of these molecules, however, have hardly been studied. This study aims to assess the prognostic significance of circulating PD-L1 and...

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Detalles Bibliográficos
Autores principales: Sideras, Kostandinos, de Man, Robert A., Harrington, Susan M., Polak, Wojciech G., Zhou, Guoying, Schutz, Hannah M., Pedroza-Gonzalez, Alexander, Biermann, Katharina, Mancham, Shanta, Hansen, Bettina E., Bart Takkenberg, R., van Vuuren, Anneke J., Pan, Qiuwei, Ijzermans, Jan N. M., Sleijfer, Stefan, Sprengers, Dave, Dong, Haidong, Kwekkeboom, Jaap, Bruno, Marco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650499/
https://www.ncbi.nlm.nih.gov/pubmed/31337865
http://dx.doi.org/10.1038/s41598-019-47235-z