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Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment

The filoviruses are etiological agents of life-threatening hemorrhagic fever with high mortality rate and risk of potential outbreak. Among members of this family, the Ebola (EBOV), Sudan (SUDV), and Marburg (MARV) viruses are considered the most pathogenic for humans. The ebolavirus nucleoprotein (...

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Detalles Bibliográficos
Autores principales: Landeras-Bueno, Sara, Oda, Shun-ichiro, Norris, Michael J., Li Salie, Zhe, Guenaga, Javier, Wyatt, Richard T., Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650547/
https://www.ncbi.nlm.nih.gov/pubmed/31337716
http://dx.doi.org/10.1128/mBio.00734-19