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Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU) family that antagonize interferon (IFN) produ...

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Detalles Bibliográficos
Autores principales: Scholte, Florine E. M., Hua, Brian L., Spengler, Jessica R., Dzimianski, John V., Coleman-McCray, JoAnn D., Welch, Stephen R., McMullan, Laura K., Nichol, Stuart T., Pegan, Scott D., Spiropoulou, Christina F., Bergeron, Éric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650548/
https://www.ncbi.nlm.nih.gov/pubmed/31337717
http://dx.doi.org/10.1128/mBio.01065-19