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Hepatitis C Virus Induces the Ubiquitin-Editing Enzyme A20 via Depletion of the Transcription Factor Upstream Stimulatory Factor 1 To Support Its Replication

Tumor necrosis factor alpha-induced protein 3 (TNFAIP3), also known as A20, is a ubiquitin-editing enzyme capable of ubiquitination or deubiquitination of its target proteins. In this study, we show that hepatitis C virus (HCV) infection could induce the expression of A20 via the activation of the A...

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Detalles Bibliográficos
Autores principales: Lee, Jiyoung, Chan, Stephanie T., Kim, Ja Yeon, Ou, Jing-hsiung James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650561/
https://www.ncbi.nlm.nih.gov/pubmed/31337730
http://dx.doi.org/10.1128/mBio.01660-19