Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat

Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix(®) or Chantix(®)), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to a portion of smokers. Smokers differ in th...

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Detalles Bibliográficos
Autores principales: Garcia-Rivas, Vernon, Fiancette, Jean-François, Cannella, Nazzareno, Carbo-Gas, Maria, Renault, Prisca, Tostain, Jessica, Deroche-Gamonet, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650579/
https://www.ncbi.nlm.nih.gov/pubmed/31379531
http://dx.doi.org/10.3389/fnbeh.2019.00159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650579/
https://www.ncbi.nlm.nih.gov/pubmed/31379531
http://dx.doi.org/10.3389/fnbeh.2019.00159

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