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Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat
Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix(®) or Chantix(®)), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to a portion of smokers. Smokers differ in th...
Autores principales: | Garcia-Rivas, Vernon, Fiancette, Jean-François, Cannella, Nazzareno, Carbo-Gas, Maria, Renault, Prisca, Tostain, Jessica, Deroche-Gamonet, Véronique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650579/ https://www.ncbi.nlm.nih.gov/pubmed/31379531 http://dx.doi.org/10.3389/fnbeh.2019.00159 |
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