Cargando…

Citrate anion improves chronic dialysis efficacy, reduces systemic inflammation and prevents Chemerin-mediated microvascular injury

Systemic inflammation and uremic toxins (UT) determine the increased cardiovascular mortality observed in chronic hemodialysis (HD) patients. Among UT, the adipokine Chemerin induces vascular dysfunction by targeting both endothelial and vascular smooth muscular cells (EC and VSMC). As Citrate anion...

Descripción completa

Detalles Bibliográficos
Autores principales: Dellepiane, Sergio, Medica, Davide, Guarena, Cesare, Musso, Tiziana, Quercia, Alessandro Domenico, Leonardi, Gianluca, Marengo, Marita, Migliori, Massimiliano, Panichi, Vincenzo, Biancone, Luigi, Pizzarelli, Francesco, Camussi, Giovanni, Cantaluppi, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650610/
https://www.ncbi.nlm.nih.gov/pubmed/31337804
http://dx.doi.org/10.1038/s41598-019-47040-8