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A critical role of autophagy in regulating the mesenchymal transition of ductular cells in liver cirrhosis

Our previous studies have shown that autophagy mediates the link between ductular reaction (DR) and liver cirrhosis. Whether the subsequent fibrogenic response is regulated by increased autophagy in DR remains unclear. Here, using both human liver specimens and a rat model of liver cirrhosis induced...

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Detalles Bibliográficos
Autores principales: Hung, Tzu-Min, Huang, Yu-Jen, Lin, Yu-Chun, Chen, Yu-Hsuan, Wu, Yao-Ming, Lee, Po-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650611/
https://www.ncbi.nlm.nih.gov/pubmed/31337842
http://dx.doi.org/10.1038/s41598-019-46764-x