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EGF Receptor Stalls upon Activation as Evidenced by Complementary Fluorescence Correlation Spectroscopy and Fluorescence Recovery after Photobleaching Measurements

To elucidate the molecular details of the activation-associated clustering of epidermal growth factor receptors (EGFRs), the time course of the mobility and aggregation states of eGFP tagged EGFR in the membranes of Chinese hamster ovary (CHO) cells was assessed by in situ mobility assays. Fluoresce...

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Detalles Bibliográficos
Autores principales: Vámosi, György, Friedländer-Brock, Elza, Ibrahim, Shehu M., Brock, Roland, Szöllősi, János, Vereb, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650801/
https://www.ncbi.nlm.nih.gov/pubmed/31323980
http://dx.doi.org/10.3390/ijms20133370