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Identification of Pyrvinium, an Anthelmintic Drug, as a Novel Anti-Adipogenic Compound Based on the Gene Expression Microarray and Connectivity Map

Obesity is a serious health problem, while the current anti-obesity drugs are not very effective. The Connectivity Map (C-Map), an in-silico drug screening approach based on gene expression profiles, has recently been indicated as a promising strategy for drug repositioning. In this study, we perfor...

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Detalles Bibliográficos
Autores principales: Wang, Zonggui, Dai, Zhong, Luo, Zhicong, Zuo, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650900/
https://www.ncbi.nlm.nih.gov/pubmed/31261664
http://dx.doi.org/10.3390/molecules24132391