Metformin Enhances Nomegestrol Acetate Suppressing Growth of Endometrial Cancer Cells and May Correlate to Downregulating mTOR Activity In Vitro and In Vivo

This study investigated the effect of a novel progestin and its combination with metformin on the growth of endometrial cancer (EC) cells. Inhibitory effects of four progestins, including nomegestrol acetate (NOMAC), medroxyprogesterone acetate, levonorgestrel, and cyproterone acetate, were evaluate...

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Detalles Bibliográficos
Autores principales: Cao, Can, Zhou, Jie-yun, Xie, Shu-wu, Guo, Xiang-jie, Li, Guo-ting, Gong, Yi-juan, Yang, Wen-jie, Li, Zhao, Zhong, Rui-hua, Shao, Hai-hao, Zhu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650946/
https://www.ncbi.nlm.nih.gov/pubmed/31284427
http://dx.doi.org/10.3390/ijms20133308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650946/
https://www.ncbi.nlm.nih.gov/pubmed/31284427
http://dx.doi.org/10.3390/ijms20133308

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