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Metformin Enhances Nomegestrol Acetate Suppressing Growth of Endometrial Cancer Cells and May Correlate to Downregulating mTOR Activity In Vitro and In Vivo
This study investigated the effect of a novel progestin and its combination with metformin on the growth of endometrial cancer (EC) cells. Inhibitory effects of four progestins, including nomegestrol acetate (NOMAC), medroxyprogesterone acetate, levonorgestrel, and cyproterone acetate, were evaluate...
Autores principales: | Cao, Can, Zhou, Jie-yun, Xie, Shu-wu, Guo, Xiang-jie, Li, Guo-ting, Gong, Yi-juan, Yang, Wen-jie, Li, Zhao, Zhong, Rui-hua, Shao, Hai-hao, Zhu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650946/ https://www.ncbi.nlm.nih.gov/pubmed/31284427 http://dx.doi.org/10.3390/ijms20133308 |
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