The Significance of IL-36 Hyperactivation and IL-36R Targeting in Psoriasis

Psoriasis is an immune-mediated inflammatory skin disease that involves mainly T helper (Th)17, Th1 and Th22 lymphocytes, which cause hyper-proliferation of the epidermis with aberrant differentiation of keratinocytes, and local production of chemokines and cytokines. These fuel a self-amplifying lo...

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Detalles Bibliográficos
Autores principales: Madonna, Stefania, Girolomoni, Giampiero, Dinarello, Charles A., Albanesi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650959/
https://www.ncbi.nlm.nih.gov/pubmed/31284527
http://dx.doi.org/10.3390/ijms20133318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650959/
https://www.ncbi.nlm.nih.gov/pubmed/31284527
http://dx.doi.org/10.3390/ijms20133318

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