OCT4 Silencing Triggers Its Epigenetic Repression and Impairs the Osteogenic and Adipogenic Differentiation of Mesenchymal Stromal Cells

Mechanisms mediating mesenchymal stromal/stem cells’ (MSCs) multipotency are unclear. Although the expression of the pluripotency factor OCT4 has been detected in MSCs, whether it has a functional role in adult stem cells is still controversial. We hypothesized that a physiological expression level...

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Detalles Bibliográficos
Autores principales: Malvicini, Ricardo, Santa-Cruz, Diego, Pacienza, Natalia, Yannarelli, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651015/
https://www.ncbi.nlm.nih.gov/pubmed/31277213
http://dx.doi.org/10.3390/ijms20133268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651015/
https://www.ncbi.nlm.nih.gov/pubmed/31277213
http://dx.doi.org/10.3390/ijms20133268

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