A Pilot Study towards the Impact of Type 2 Diabetes on the Expression and Activities of Drug Metabolizing Enzymes and Transporters in Human Duodenum

To characterize effects of type 2 diabetes (T2D) on mRNA expression levels for 10 Cytochromes P450 (CYP450s), two carboxylesterases, and three drug transporters (ABCB1, ABCG2, SLCO2B1) in human duodenal biopsies. To compare drug metabolizing enzyme activities of four CYP450 isoenzymes in duodenal bi...

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Detalles Bibliográficos
Autores principales: Gravel, Sophie, Panzini, Benoit, Belanger, Francois, Turgeon, Jacques, Michaud, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651059/
https://www.ncbi.nlm.nih.gov/pubmed/31269743
http://dx.doi.org/10.3390/ijms20133257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651059/
https://www.ncbi.nlm.nih.gov/pubmed/31269743
http://dx.doi.org/10.3390/ijms20133257

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