Preparation and In Vitro/In Vivo Characterization of Polymeric Nanoparticles Containing Methotrexate to Improve Lymphatic Delivery

Methotrexate (MTX) is a folic acid antagonist used as an effective drug to treat various kinds of cancers. However, MTX has limited use in cancer chemotherapy due to its adverse effects such as poor bioavailability, low specificity, drug resistance, and dose-dependent side effects. To improve lympha...

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Detalles Bibliográficos
Autores principales: Jang, Ji-Hun, Jeong, Seung-Hyun, Lee, Yong-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651109/
https://www.ncbi.nlm.nih.gov/pubmed/31284483
http://dx.doi.org/10.3390/ijms20133312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651109/
https://www.ncbi.nlm.nih.gov/pubmed/31284483
http://dx.doi.org/10.3390/ijms20133312

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