Cargando…

Preparation and In Vitro/In Vivo Characterization of Polymeric Nanoparticles Containing Methotrexate to Improve Lymphatic Delivery

Methotrexate (MTX) is a folic acid antagonist used as an effective drug to treat various kinds of cancers. However, MTX has limited use in cancer chemotherapy due to its adverse effects such as poor bioavailability, low specificity, drug resistance, and dose-dependent side effects. To improve lympha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Ji-Hun, Jeong, Seung-Hyun, Lee, Yong-Bok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651109/ https://www.ncbi.nlm.nih.gov/pubmed/31284483 http://dx.doi.org/10.3390/ijms20133312

Ejemplares similares

Enhanced Lymphatic Delivery of Methotrexate Using W/O/W Nanoemulsion: In Vitro Characterization and Pharmacokinetic Study
por: Jang, Ji-Hun, et al.
Publicado: (2020)

Pharmacokinetic Comparison between Methotrexate-Loaded Nanoparticles and Nanoemulsions as Hard- and Soft-Type Nanoformulations: A Population Pharmacokinetic Modeling Approach
por: Jeong, Seung-Hyun, et al.
Publicado: (2021)

Fabrication of Polymeric Hydrogels Containing Esomeprazole for Oral Delivery: In Vitro and In Vivo Pharmacokinetic Characterization
por: Ullah, Irshad, et al.
Publicado: (2023)

Polymeric nanoparticles containing diazepam: preparation, optimization, characterization, in-vitro drug release and release kinetic study
por: Bohrey, Sarvesh, et al.
Publicado: (2016)

PLGA nanoparticles for the oral delivery of nuciferine: preparation, physicochemical characterization and in vitro/in vivo studies
por: Liu, Ying, et al.
Publicado: (2017)

Preparation and physicochemical studies on polymeric nanocomposites containing copper oxide nanoparticles
por: Alsheheri, Soad, et al.
Publicado: (2023)

Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo
por: Zhao, Yanna, et al.
Publicado: (2016)

Targeting Lymphatics for Nanoparticle Drug Delivery
por: McCright, Jacob, et al.
Publicado: (2022)

Novel, Blended Polymeric Microspheres for the Controlled Release of Methotrexate: Characterization and In Vivo Antifibrotic Studies
por: Nabai, Layla, et al.
Publicado: (2023)

Preparation and optimization of polymeric micelles as an oral drug delivery system for deferoxamine mesylate: in vitro and ex vivo studies
por: Salimi, Anayatollah, et al.
Publicado: (2019)

Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo
por: Guerrero-Cázares, Hugo, et al.
Publicado: (2014)

Ascorbic acid tethered polymeric nanoparticles enable efficient brain delivery of galantamine: An in vitro-in vivo study
por: Gajbhiye, Kavita R., et al.
Publicado: (2017)

Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

Drug delivery to the brain via the nasal route of administration: exploration of key targets and major consideration factors
por: Jeong, Seung-Hyun, et al.
Publicado: (2022)

Preparation and Characterization of Gelatin Nanofibers Containing Silver Nanoparticles
por: Jeong, Lim, et al.
Publicado: (2014)

Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo Evaluation
por: Sharma, Deepak, et al.
Publicado: (2014)

Polymeric nanoparticles for RNA delivery
por: Jiang, Xingya, et al.
Publicado: (2021)

Preparation and assessment of chitosan-coated superparamagnetic Fe(3)O(4) nanoparticles for controlled delivery of methotrexate
por: Mohammadi-Samani, S., et al.
Publicado: (2013)

Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo
por: Wang, Mingxing, et al.
Publicado: (2020)

Polymeric Mesoporous Silica Nanoparticles for Enhanced Delivery of 5-Fluorouracil In Vitro
por: Moodley, Thashini, et al.
Publicado: (2019)

Polymeric Inserts Containing Eudragit(®) L100 Nanoparticle for Improved Ocular Delivery of Azithromycin
por: Taghe, Shiva, et al.
Publicado: (2020)

Polymeric Nanoparticles Containing Both Antigen and Vitamin D(3) Induce Antigen-Specific Immune Suppression
por: Jung, Ho-Hyun, et al.
Publicado: (2019)

Novel Pastes Containing Polymeric Nanoparticles for Dentin Hypersensitivity Treatment: An In Vitro Study
por: Toledano-Osorio, Manuel, et al.
Publicado: (2021)

Enhanced Oral Delivery of Docetaxel Using Thiolated Chitosan Nanoparticles: Preparation, In Vitro and In Vivo Studies
por: Saremi, Shahrooz, et al.
Publicado: (2013)

Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro
por: Vieira, Débora B, et al.
Publicado: (2008)

Convection-enhanced delivery of methotrexate-loaded maghemite nanoparticles
por: Corem-Salkmon, Enav, et al.
Publicado: (2011)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization
por: Kola Srinivas, Navya Sree, et al.
Publicado: (2016)

Inhalable Polymeric Nanoparticles for Pulmonary Delivery of Antimicrobial Peptide SET-M33: Antibacterial Activity and Toxicity In Vitro and In Vivo
por: Cresti, Laura, et al.
Publicado: (2022)

Solid Lipid Nanoparticles Containing Morin: Preparation, Characterization, and Ex Vivo Permeation Studies
por: De Gaetano, Federica, et al.
Publicado: (2023)

Polymeric Nanoparticles Properties and Brain Delivery
por: Ribovski, Laís, et al.
Publicado: (2021)

Polymeric Nanoparticles for Drug Delivery in Osteoarthritis
por: Pontes, Adriano P., et al.
Publicado: (2022)

Preparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary delivery
por: Sinsuebpol, Chutima, et al.
Publicado: (2013)

Effective mucoadhesive liposomal delivery system for risedronate: preparation and in vitro/in vivo characterization
por: Jung, Il-Woo, et al.
Publicado: (2014)

Hydrogel Containing Solid Lipid Nanoparticles Loaded with Argan Oil and Simvastatin: Preparation, In Vitro and Ex Vivo Assessment
por: Khan, Muhammad Farhan Ali, et al.
Publicado: (2022)

Preparation, In Vitro Characterization, and In Vivo Pharmacokinetic Evaluation of Respirable Porous Microparticles Containing Rifampicin
por: Kundawala, Aliasgar, et al.
Publicado: (2014)

Microfluidic preparation of monodisperse polymeric microspheres coated with silica nanoparticles
por: Kim, Dong-Yeong, et al.
Publicado: (2018)

Optimized Preparation of Levofloxacin Loaded Polymeric Nanoparticles
por: López-López, Manuel, et al.
Publicado: (2019)

Composite Polylactic-Methacrylic Acid Copolymer Nanoparticles for the Delivery of Methotrexate
por: Sibeko, Bongani, et al.
Publicado: (2012)

Paradoxical response of malignant melanoma to methotrexate in vivo and in vitro.
por: Gaukroger, J., et al.
Publicado: (1983)

Cannot write session to /tmp/vufind_sessions/sess_282d944qtjntstnkfv5sqhuuup