New HSV-1 Anti-Viral 1′-Homocarbocyclic Nucleoside Analogs with an Optically Active Substituted Bicyclo[2.2.1]Heptane Fragment as a Glycoside Moiety

New 1′-homocarbanucleoside analogs with an optically active substituted bicyclo[2.2.1]heptane skeleton as sugar moiety were synthesized. The pyrimidine analogs with uracil, 5-fluorouracil, thymine and cytosine and key intermediate with 6-chloropurine (5) as nucleobases were synthesized by a selectiv...

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Detalles Bibliográficos
Autores principales: Tănase, Constantin I., Drăghici, Constantin, Hanganu, Anamaria, Pintilie, Lucia, Maganu, Maria, Volobueva, Alexandrina, Sinegubova, Ekaterina, Zarubaev, Vladimir V., Neyts, Johan, Jochmans, Dirk, Slita, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651170/
https://www.ncbi.nlm.nih.gov/pubmed/31277334
http://dx.doi.org/10.3390/molecules24132446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651170/
https://www.ncbi.nlm.nih.gov/pubmed/31277334
http://dx.doi.org/10.3390/molecules24132446

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