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The Dualistic Effect of COX-2-Mediated Signaling in Obesity and Insulin Resistance

Obesity and insulin resistance are two major risk factors for the development of metabolic syndrome, type 2 diabetes and associated cardiovascular diseases (CVDs). Cyclooxygenase (COX), a rate-limiting enzyme responsible for the biosynthesis of prostaglandins (PGs), exists in two isoforms: COX-1, th...

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Detalles Bibliográficos
Autores principales: Chan, Pei-Chi, Liao, Min-Tser, Hsieh, Po-Shiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651192/
https://www.ncbi.nlm.nih.gov/pubmed/31247902
http://dx.doi.org/10.3390/ijms20133115