Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation

In recent years, first evidences emerged that sympathetic neurotransmitters influence osteoarthritis (OA) manifestation. Joint-resident stem cells might contribute to cartilage repair, however, their chondrogenic function is reduced. The neurotransmitter norepinephrine (NE) was detected in the synov...

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Detalles Bibliográficos
Autores principales: El Bagdadi, Karima, Zaucke, Frank, Meurer, Andrea, Straub, Rainer H., Jenei-Lanzl, Zsuzsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651223/
https://www.ncbi.nlm.nih.gov/pubmed/31248037
http://dx.doi.org/10.3390/ijms20133127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651223/
https://www.ncbi.nlm.nih.gov/pubmed/31248037
http://dx.doi.org/10.3390/ijms20133127

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