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Norepinephrine Inhibits Synovial Adipose Stem Cell Chondrogenesis via α2a-Adrenoceptor-Mediated ERK1/2 Activation
In recent years, first evidences emerged that sympathetic neurotransmitters influence osteoarthritis (OA) manifestation. Joint-resident stem cells might contribute to cartilage repair, however, their chondrogenic function is reduced. The neurotransmitter norepinephrine (NE) was detected in the synov...
Autores principales: | El Bagdadi, Karima, Zaucke, Frank, Meurer, Andrea, Straub, Rainer H., Jenei-Lanzl, Zsuzsa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651223/ https://www.ncbi.nlm.nih.gov/pubmed/31248037 http://dx.doi.org/10.3390/ijms20133127 |
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