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Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4′-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis, largely due to resistance to current radiotherapy and Temozolomide chemotherapy. The constitutive activation of Signal Transducer and Activator of Transcription 3 (STAT3) is evidenced as a pivotal driver of...

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Detalles Bibliográficos
Autores principales: Cheng, Yen-Po, Li, Shiming, Chuang, Wan-Ling, Li, Chia-Hsuan, Chen, Guan-Jun, Chang, Ching-Chin, Or, Chi-Hung R., Lin, Ping-Yi, Chang, Chia-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651290/
https://www.ncbi.nlm.nih.gov/pubmed/31323961
http://dx.doi.org/10.3390/ijms20133366