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Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4′-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis, largely due to resistance to current radiotherapy and Temozolomide chemotherapy. The constitutive activation of Signal Transducer and Activator of Transcription 3 (STAT3) is evidenced as a pivotal driver of...
Autores principales: | Cheng, Yen-Po, Li, Shiming, Chuang, Wan-Ling, Li, Chia-Hsuan, Chen, Guan-Jun, Chang, Ching-Chin, Or, Chi-Hung R., Lin, Ping-Yi, Chang, Chia-Che |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651290/ https://www.ncbi.nlm.nih.gov/pubmed/31323961 http://dx.doi.org/10.3390/ijms20133366 |
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