Loss of Mevalonate/Cholesterol Homeostasis in the Brain: A Focus on Autism Spectrum Disorder and Rett Syndrome

The mevalonate (MVA)/cholesterol pathway is crucial for central nervous system (CNS) development and function and consequently, any dysfunction of this fundamental metabolic pathway is likely to provoke pathologic changes in the brain. Mutations in genes directly involved in MVA/cholesterol metaboli...

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Detalles Bibliográficos
Autores principales: Segatto, Marco, Tonini, Claudia, Pfrieger, Frank W., Trezza, Viviana, Pallottini, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651320/
https://www.ncbi.nlm.nih.gov/pubmed/31284522
http://dx.doi.org/10.3390/ijms20133317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651320/
https://www.ncbi.nlm.nih.gov/pubmed/31284522
http://dx.doi.org/10.3390/ijms20133317

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