Carboplatin Enhances the Activity of Human Transient Receptor Potential Ankyrin 1 through the Cyclic AMP-Protein Kinase A-A-Kinase Anchoring Protein (AKAP) Pathways

Carboplatin, an anticancer drug, often causes chemotherapy-induced peripheral neuropathy (PN). Transient receptor potential ankyrin 1 (TRPA1), a non-selective cation channel, is a polymodal nociceptor expressed in sensory neurons. TRPA1 is not only involved in pain transmission, but also in allodyni...

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Detalles Bibliográficos
Autores principales: Miyano, Kanako, Shiraishi, Seiji, Minami, Koichiro, Sudo, Yuka, Suzuki, Masami, Yokoyama, Toru, Terawaki, Kiyoshi, Nonaka, Miki, Murata, Hiroaki, Higami, Yoshikazu, Uezono, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651390/
https://www.ncbi.nlm.nih.gov/pubmed/31277262
http://dx.doi.org/10.3390/ijms20133271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651390/
https://www.ncbi.nlm.nih.gov/pubmed/31277262
http://dx.doi.org/10.3390/ijms20133271

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