The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage. However, the aberrant activation of the NLRP3 inflammasome has been linked...

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Detalles Bibliográficos
Autores principales: Kelley, Nathan, Jeltema, Devon, Duan, Yanhui, He, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651423/
https://www.ncbi.nlm.nih.gov/pubmed/31284572
http://dx.doi.org/10.3390/ijms20133328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651423/
https://www.ncbi.nlm.nih.gov/pubmed/31284572
http://dx.doi.org/10.3390/ijms20133328

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