A Novel HIF Inhibitor Halofuginone Prevents Neurodegeneration in a Murine Model of Retinal Ischemia-Reperfusion

Neurodegeneration caused with retinal ischemia or high intraocular pressure is irreversible in general. We have focused on the role of hypoxia-inducible factor (HIF) in retinal homeostasis and revealed that HIF inhibition may be effective against retinal neovascular and neurodegeneration. In this st...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunimi, Hiromitsu, Miwa, Yukihiro, Inoue, Hiroyoshi, Tsubota, Kazuo, Kurihara, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651456/
https://www.ncbi.nlm.nih.gov/pubmed/31261724
http://dx.doi.org/10.3390/ijms20133171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651456/
https://www.ncbi.nlm.nih.gov/pubmed/31261724
http://dx.doi.org/10.3390/ijms20133171

Ejemplares similares