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A Novel HIF Inhibitor Halofuginone Prevents Neurodegeneration in a Murine Model of Retinal Ischemia-Reperfusion

Neurodegeneration caused with retinal ischemia or high intraocular pressure is irreversible in general. We have focused on the role of hypoxia-inducible factor (HIF) in retinal homeostasis and revealed that HIF inhibition may be effective against retinal neovascular and neurodegeneration. In this st...

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Detalles Bibliográficos
Autores principales:	Kunimi, Hiromitsu, Miwa, Yukihiro, Inoue, Hiroyoshi, Tsubota, Kazuo, Kurihara, Toshihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651456/ https://www.ncbi.nlm.nih.gov/pubmed/31261724 http://dx.doi.org/10.3390/ijms20133171

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