Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration

Background: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders involving devastating loss of dopaminergic neurons in the substantia nigra. Early steps in PD pathogenesis include mitochondrial dysfunction, and mutations in mitochondrial genes have been linked to familial f...

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Detalles Bibliográficos
Autores principales: Hartman, Jessica H., Gonzalez-Hunt, Claudia, Hall, Samantha M., Ryde, Ian T., Caldwell, Kim A., Caldwell, Guy A., Meyer, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651461/
https://www.ncbi.nlm.nih.gov/pubmed/31261893
http://dx.doi.org/10.3390/ijms20133202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651461/
https://www.ncbi.nlm.nih.gov/pubmed/31261893
http://dx.doi.org/10.3390/ijms20133202

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