Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

Cystathionine-γ-lyase (CSE) is a hydrogen sulfide (H(2)S)-synthesizing enzyme that promotes inflammation by upregulating H(2)S in sepsis. Liver sinusoidal endothelial cells (LSECs) are fenestrated endothelial cells (liver sieve) that undergo alteration during sepsis and H(2)S plays a role in this pr...

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Detalles Bibliográficos
Autores principales: Gaddam, Ravinder R, Chambers, Stephen, Fraser, Robin, Cogger, Victoria C, Le Couteur, David G, Ishii, Isao, Bhatia, Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651477/
https://www.ncbi.nlm.nih.gov/pubmed/31261857
http://dx.doi.org/10.3390/ijms20133191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651477/
https://www.ncbi.nlm.nih.gov/pubmed/31261857
http://dx.doi.org/10.3390/ijms20133191

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