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Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

Cystathionine-γ-lyase (CSE) is a hydrogen sulfide (H(2)S)-synthesizing enzyme that promotes inflammation by upregulating H(2)S in sepsis. Liver sinusoidal endothelial cells (LSECs) are fenestrated endothelial cells (liver sieve) that undergo alteration during sepsis and H(2)S plays a role in this pr...

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Detalles Bibliográficos
Autores principales:	Gaddam, Ravinder R, Chambers, Stephen, Fraser, Robin, Cogger, Victoria C, Le Couteur, David G, Ishii, Isao, Bhatia, Madhav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651477/ https://www.ncbi.nlm.nih.gov/pubmed/31261857 http://dx.doi.org/10.3390/ijms20133191

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