Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles

The O-heterocycles, benzo-1,4-dioxane, phthalan, isochroman, 2,3-dihydrobenzofuran, benzofuran, and dibenzofuran are important building blocks with considerable medical application for the production of pharmaceuticals. Cytochrome P450 monooxygenase (P450) Bacillus megaterium 3 (BM3) wild type (WT)...

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Detalles Bibliográficos
Autores principales: Santos, Gustavo de Almeida, Dhoke, Gaurao V., Davari, Mehdi D., Ruff, Anna Joëlle, Schwaneberg, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651506/
https://www.ncbi.nlm.nih.gov/pubmed/31288417
http://dx.doi.org/10.3390/ijms20133353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651506/
https://www.ncbi.nlm.nih.gov/pubmed/31288417
http://dx.doi.org/10.3390/ijms20133353

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