mRNA Engineering for the Efficient Chaperone-Mediated Co-Translational Folding of Recombinant Proteins in Escherichia coli

The production of soluble, functional recombinant proteins by engineered bacterial hosts is challenging. Natural molecular chaperone systems have been used to solubilize various recombinant proteins with limited success. Here, we attempted to facilitate chaperone-mediated folding by directing the mo...

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Detalles Bibliográficos
Autores principales: Bui, Le Minh, Geraldi, Almando, Nguyen, Thi Thuy, Lee, Jun Hyoung, Lee, Ju Young, Cho, Byung-Kwan, Kim, Sun Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651523/
https://www.ncbi.nlm.nih.gov/pubmed/31261687
http://dx.doi.org/10.3390/ijms20133163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651523/
https://www.ncbi.nlm.nih.gov/pubmed/31261687
http://dx.doi.org/10.3390/ijms20133163

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