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Cathepsin L Inhibitors with Activity against the Liver Fluke Identified From a Focus Library of Quinoxaline 1,4-di-N-Oxide Derivatives

Infections caused by Fasciola species are widely distributed in cattle and sheep causing significant economic losses, and are emerging as human zoonosis with increasing reports of human cases, especially in children in endemic areas. The current treatment is chemotherapeutic, triclabendazole being t...

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Detalles Bibliográficos
Autores principales: Ferraro, Florencia, Merlino, Alicia, Gil, Jorge, Cerecetto, Hugo, Corvo, Ileana, Cabrera, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651555/
https://www.ncbi.nlm.nih.gov/pubmed/31247891
http://dx.doi.org/10.3390/molecules24132348