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(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase

Foot-and-mouth disease virus (FMDV) is an RNA virus belonging to the Picornaviridae family that contains three small viral proteins (VPgs), named VPg1, VPg2 and VPg3, linked to the 5′-end of the viral genome. These VPg proteins act as primers for RNA replication, which is initiated by the consecutiv...

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Detalles Bibliográficos
Autores principales: de Castro, Sonia, Ferrer-Orta, Cristina, Mills, Alberto, Fernández-Cureses, Gloria, Gago, Federico, Verdaguer, Nuria, Camarasa, María-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651598/
https://www.ncbi.nlm.nih.gov/pubmed/31247979
http://dx.doi.org/10.3390/molecules24132360