Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis

Several cytochrome P450 enzymes (CYPs) encoded in the genome of Mycobacterium tuberculosis (Mtb) are considered potential new drug targets due to the essential roles they play in bacterial viability and in the establishment of chronic intracellular infection. Identification of inhibitors of Mtb CYPs...

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Detalles Bibliográficos
Autores principales: Ortega Ugalde, Sandra, Ma, Dongping, Cali, James J., Commandeur, Jan N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651611/
https://www.ncbi.nlm.nih.gov/pubmed/31208248
http://dx.doi.org/10.1177/2472555219853220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651611/
https://www.ncbi.nlm.nih.gov/pubmed/31208248
http://dx.doi.org/10.1177/2472555219853220

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