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S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells

Chronic inflammation and angiogenesis are associated with colonic carcinogenesis. Enteric glia-derived S100B protein has been proposed as an “ideal bridge”, linking colonic inflammation and cancer, given its dual ability to up-regulate nuclear factor-kappaB (NF-κB) transcription via receptor for adv...

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Detalles Bibliográficos
Autores principales: Seguella, Luisa, Capuano, Riccardo, Pesce, Mirella, Annunziata, Giuseppe, Pesce, Marcella, de Conno, Barbara, Sarnelli, Giovanni, Aurino, Laura, Esposito, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651655/
https://www.ncbi.nlm.nih.gov/pubmed/31266264
http://dx.doi.org/10.3390/ijms20133240