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Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs)

This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations. These mutations in specific genes generate premature termination codons (PTCs) respons...

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Detalles Bibliográficos
Autores principales:	Campofelice, Ambra, Lentini, Laura, Di Leonardo, Aldo, Melfi, Raffaella, Tutone, Marco, Pace, Andrea, Pibiri, Ivana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651739/ https://www.ncbi.nlm.nih.gov/pubmed/31284579 http://dx.doi.org/10.3390/ijms20133329

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