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Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

The Insulin-like growth factor (IGF) axis is one of the best-established drivers of thyroid transformation, as thyroid cancer cells overexpress both IGF ligands and their receptors. Thyroid neoplasms encompass distinct clinical and biological entities as differentiated thyroid carcinomas (DTC)—compr...

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Detalles Bibliográficos
Autores principales: Manzella, Livia, Massimino, Michele, Stella, Stefania, Tirrò, Elena, Pennisi, Maria Stella, Martorana, Federica, Motta, Gianmarco, Vitale, Silvia Rita, Puma, Adriana, Romano, Chiara, Di Gregorio, Sandra, Russo, Marco, Malandrino, Pasqualino, Vigneri, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651760/
https://www.ncbi.nlm.nih.gov/pubmed/31269742
http://dx.doi.org/10.3390/ijms20133258