PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein–Protein Interactions

Phosphoprotein enriched in astrocytes, 15 kDa (PEA-15) exerts its regulatory roles on several critical cellular pathways through protein–protein interactions depending on its phosphorylation states. It can either inhibit the extracellular signal-regulated kinase (ERK) activities when it is dephospho...

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Detalles Bibliográficos
Autores principales: Crespo-Flores, Sergio L., Cabezas, Andres, Hassan, Sherouk, Wei, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651876/
https://www.ncbi.nlm.nih.gov/pubmed/31284641
http://dx.doi.org/10.3390/ijms20133335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651876/
https://www.ncbi.nlm.nih.gov/pubmed/31284641
http://dx.doi.org/10.3390/ijms20133335

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