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A-to-I editing of Malacoherpesviridae RNAs supports the antiviral role of ADAR1 in mollusks

BACKGROUND: Adenosine deaminase enzymes of the ADAR family are conserved in metazoans. They convert adenine into inosine in dsRNAs and thus alter both structural properties and the coding potential of their substrates. Acting on exogenous dsRNAs, ADAR1 exerts a pro- or anti-viral role in vertebrates...

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Detalles Bibliográficos
Autores principales: Rosani, Umberto, Bai, Chang-Ming, Maso, Lorenzo, Shapiro, Maxwell, Abbadi, Miriam, Domeneghetti, Stefania, Wang, Chong-Ming, Cendron, Laura, MacCarthy, Thomas, Venier, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651903/
https://www.ncbi.nlm.nih.gov/pubmed/31337330
http://dx.doi.org/10.1186/s12862-019-1472-6