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Metformin reverses mesenchymal phenotype of primary breast cancer cells through STAT3/NF-κB pathways

BACKGROUND: Breast cancer currently is the most frequently diagnosed neoplasm and the leading cause of death from cancer in women worldwide, which is mainly due to metastatic disease. Increasing our understanding of the molecular mechanisms leading to metastasis might thus improve the pharmacologica...

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Detalles Bibliográficos
Autores principales: Esparza-López, José, Alvarado-Muñoz, Juan Francisco, Escobar-Arriaga, Elizabeth, Ulloa-Aguirre, Alfredo, de Jesús Ibarra-Sánchez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651945/
https://www.ncbi.nlm.nih.gov/pubmed/31337349
http://dx.doi.org/10.1186/s12885-019-5945-1