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A single-arm pilot study of metformin in patients with autosomal dominant polycystic kidney disease
BACKGROUND: Metformin has shown promising results regarding cystogenesis inhibition in preclinical studies with autosomal dominant polycystic kidney disease (ADPKD) models. We designed a prospective, preliminary, single-arm study to evaluate the tolerability, safety and the effect of Metformin on ki...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651959/ https://www.ncbi.nlm.nih.gov/pubmed/31337351 http://dx.doi.org/10.1186/s12882-019-1463-2 |