Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy outcome in metastatic melanoma

BACKGROUND: The cancer-associated fibroblast (CAF) population is implicated in immune dysregulation. Here, we test the hypothesis that CAF profiles in pretreatment tumor specimens are associated with response to immune checkpoint blockade of programmed cell death 1 (PD-1). METHODS: Pretreatment whol...

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Detalles Bibliográficos
Autores principales: Wong, Pok Fai, Wei, Wei, Gupta, Swati, Smithy, James W., Zelterman, Daniel, Kluger, Harriet M., Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651990/
https://www.ncbi.nlm.nih.gov/pubmed/31337426
http://dx.doi.org/10.1186/s40425-019-0675-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651990/
https://www.ncbi.nlm.nih.gov/pubmed/31337426
http://dx.doi.org/10.1186/s40425-019-0675-0

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