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Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients

BACKGROUND: Idiopathic scoliosis (IS) is a complex disease with an unclear etiology, and the worldwide prevalence is approximately 2–3%. As an important link between environmental factors and phenotypic differences, epigenetic changes, such as lncRNA, miRNA, and DNA methylation, have recently been r...

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Detalles Bibliográficos
Autores principales: Li, Jiong, Yang, Guanteng, Liu, Shaohua, Wang, Longjie, Liang, Zhuotao, Zhang, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651996/
https://www.ncbi.nlm.nih.gov/pubmed/31337422
http://dx.doi.org/10.1186/s13148-019-0706-1