Tryptophan catabolism increases in breast cancer patients compared to healthy controls without affecting the cancer outcome or response to chemotherapy

BACKGROUND: Indoleamine 2,3-dioxygenase catalyzes the conversion of tryptophan to kynurenine, an immunosuppressive metabolite involved in T regulatory cell differentiation. Indoleamine 2,3-dioxygenase is expressed in many cancer types, including breast cancer. Here, we analyze kynurenine and tryptop...

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Detalles Bibliográficos
Autores principales: Onesti, Concetta Elisa, Boemer, François, Josse, Claire, Leduc, Stephane, Bours, Vincent, Jerusalem, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652004/
https://www.ncbi.nlm.nih.gov/pubmed/31337401
http://dx.doi.org/10.1186/s12967-019-1984-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652004/
https://www.ncbi.nlm.nih.gov/pubmed/31337401
http://dx.doi.org/10.1186/s12967-019-1984-2

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