Design, Synthesis, and Biological Application of Novel Photoaffinity Probes of Dihydropyridine Derivatives, BAY R3401

To explore the molecular mechanisms of BAY R3401, four types of novel photoaffinity probes bearing different secondary tags were synthesized. Their potency for glycogenolysis was evaluated in primary human liver HL-7702 cells and HepG2 cells. Probe 2d showed the best activity in primary human liver...

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Detalles Bibliográficos
Autores principales: Zhang, Liying, Yan, Zhiwei, Wang, Youde, Song, Chengjun, Miao, Guangxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652023/
https://www.ncbi.nlm.nih.gov/pubmed/31261804
http://dx.doi.org/10.3390/molecules24132394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652023/
https://www.ncbi.nlm.nih.gov/pubmed/31261804
http://dx.doi.org/10.3390/molecules24132394

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