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Vanillic Acid Restores Coenzyme Q Biosynthesis and ATP Production in Human Cells Lacking COQ6

Coenzyme Q (CoQ), a redox-active lipid, is comprised of a quinone group and a polyisoprenoid tail. It is an electron carrier in the mitochondrial respiratory chain, a cofactor of other mitochondrial dehydrogenases, and an essential antioxidant. CoQ requires a large set of enzymes for its biosynthesi...

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Detalles Bibliográficos
Autores principales: Acosta Lopez, Manuel J., Trevisson, Eva, Canton, Marcella, Vazquez-Fonseca, Luis, Morbidoni, Valeria, Baschiera, Elisa, Frasson, Chiara, Pelosi, Ludovic, Rascalou, Bérengère, Desbats, Maria Andrea, Alcázar-Fabra, María, Ríos, José Julián, Sánchez-García, Alicia, Basso, Giuseppe, Navas, Placido, Pierrel, Fabien, Brea-Calvo, Gloria, Salviati, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652073/
https://www.ncbi.nlm.nih.gov/pubmed/31379988
http://dx.doi.org/10.1155/2019/3904905